A New Urine Test for Bladder Cancer and Treatment Response
MULTIPLEXED PROTEIN BIOMARKER-BASED ASSAY FOR THE DETECTION OF BLADDER CANCER
This project is creating a new urine test to help find bladder cancer earlier and predict how well patients will respond to treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11146428 on NIH RePORTER |
What this research studies
Many people experience blood in their urine, which often leads to expensive tests to rule out bladder cancer. For those diagnosed with non-muscle-invasive bladder cancer, the disease frequently returns, and a common treatment called BCG doesn't work for everyone. This research aims to develop a test that can tell if bladder cancer is present from a simple urine sample. It also seeks to predict which patients will benefit most from BCG treatment, helping doctors make better decisions for their care.
Who could benefit from this research
Good fit: Ideal candidates for future applications of this research include individuals with microscopic blood in their urine or those diagnosed with non-muscle-invasive bladder cancer considering or undergoing BCG treatment.
Not a fit: Patients without concerns for bladder cancer or those not undergoing BCG treatment for bladder cancer would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this new test could help patients avoid unnecessary procedures, receive earlier bladder cancer diagnoses, and get the most effective treatment for their specific condition.
How similar studies have performed: The abstract indicates that a reliable test to predict BCG response or to rule out bladder cancer in patients with hematuria is not currently available, suggesting this approach is novel.
Where this research is happening
Los Angeles, United States
- Cedars-Sinai Medical Center — Los Angeles, United States (Active)
Researchers
- Principal investigator: Rosser, Charles J — Cedars-Sinai Medical Center
- Study coordinator: Rosser, Charles J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.