A new ultrasound technique to measure blood flow in patients with leg artery disease
A Contrast-free Ultrasound-based Quantitative Angio Flow Imaging Technique to Assess Peripheral Arterial Disease of Lower Limb
This study is testing a new, safe way to use ultrasound to check blood flow in the legs of people with peripheral arterial disease (PAD), helping doctors understand how well blood is moving in smaller vessels and potentially leading to better care for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10941852 on NIH RePORTER |
What this research studies
This research investigates a novel ultrasound-based method to assess blood flow in the lower limbs of patients suffering from peripheral arterial disease (PAD). The approach focuses on evaluating microcirculation, which is often overlooked in traditional assessments that mainly look for blockages in larger arteries. By using a contrast-free technique, the study aims to provide a safe and non-invasive way to measure blood flow responses to various stimuli, such as exercise. This could lead to earlier diagnosis and better management of PAD, ultimately improving patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with peripheral arterial disease, particularly those experiencing symptoms like claudication or exercise intolerance.
Not a fit: Patients without peripheral arterial disease or those with advanced stages of the disease requiring surgical intervention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic techniques for peripheral arterial disease, enabling better treatment strategies and potentially reducing the risk of severe complications like amputation.
How similar studies have performed: Previous research has shown promise in using ultrasound techniques for vascular assessments, indicating that this approach may build on established methods rather than being entirely novel.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Alizad, Azra — Mayo Clinic Rochester
- Study coordinator: Alizad, Azra
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.