A new ultrasound catheter to treat blood clots more effectively
Integrated Dual-frequency Ultrasound Catheter for Accelerated Sonothrombolysis (iDUCAS)
This study is testing a new ultrasound catheter system called iDUCAS that aims to make treating deep vein thrombosis (DVT) safer and more effective, so patients can dissolve blood clots faster and with fewer side effects.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina State University Raleigh NIH-funded |
| Lab location | 1 site (Raleigh, United States) |
| Project ID | NIH-11087661 on NIH RePORTER |
What this research studies
This research focuses on developing an advanced ultrasound catheter system called iDUCAS, designed to enhance the treatment of deep vein thrombosis (DVT). By integrating intravascular imaging and motorized catheter advancement, the iDUCAS system aims to improve the efficiency and safety of thrombolysis, which is the process of dissolving blood clots. The approach utilizes microbubbles and nanodroplets to enhance the effectiveness of ultrasound in breaking down clots, potentially reducing treatment time and minimizing side effects. Patients may benefit from a more effective and safer treatment option for DVT compared to current methods.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with deep vein thrombosis, particularly those with long retracted clots.
Not a fit: Patients with conditions unrelated to deep vein thrombosis or those who do not have blood clotting issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide patients with a faster and safer method for treating deep vein thrombosis.
How similar studies have performed: Previous research has shown promise with similar ultrasound-based approaches for thrombolysis, indicating potential for success with this novel system.
Where this research is happening
Raleigh, United States
- North Carolina State University Raleigh — Raleigh, United States (Active)
Researchers
- Principal investigator: Jiang, Xiaoning — North Carolina State University Raleigh
- Study coordinator: Jiang, Xiaoning
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.