A new type of heart valve that reduces the need for blood thinners.
SBIR Phase II: Novel Hyaluronan Enhanced Polymeric Trans-Catheter Aortic Valve
['FUNDING_SBIR_2'] · YOUNGHEARTVALVE LLC · NIH-10920901
This study is testing a new heart valve called Rejuvenate™ that aims to be a safer and easier option for people needing heart valve replacement, using special materials to help it last longer without the need for blood thinners.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YOUNGHEARTVALVE LLC (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-10920901 on ClinicalTrials.gov |
What this research studies
This research focuses on developing the Rejuvenate™ Heart Valve, a transcatheter aortic valve designed to be less invasive and more effective than traditional options. It features flexible leaflets made from a special polymer that prevents calcification and eliminates the need for long-term anticoagulation therapy. The valve uses innovative Dynamic Sealing Technology to ensure a secure fit once implanted, enhancing its performance and longevity. The project includes rigorous testing to ensure safety and effectiveness before it can be used in patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from aortic stenosis who are in need of a heart valve replacement.
Not a fit: Patients who have contraindications for transcatheter aortic valve replacement or those with other severe comorbidities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide patients with a safer and more durable heart valve option that reduces the risks associated with blood thinners.
How similar studies have performed: Other research has shown promise with similar transcatheter heart valve technologies, indicating a potential for success in this novel approach.
Where this research is happening
ATLANTA, UNITED STATES
- YOUNGHEARTVALVE LLC — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TOMBA, TODD CHARLES — YOUNGHEARTVALVE LLC
- Study coordinator: TOMBA, TODD CHARLES
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.