NIH-funded research Sbir 2 grant

A new type of battery for leadless pacemakers

Official title: Leadless Pacemaker Betavoltaic Power Source

Funded at City Labs, INC. · NIH-10429931 · Data updated 2026-11-12

This study is working on a new type of tiny battery for leadless pacemakers that could last up to 20 years, making life easier for heart patients by reducing the need for surgeries and improving their overall quality of life.

More Pacemaker research and trials

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionCity Labs, INC.
NIH-funded
Lab location1 site (Miami, UNITED STATES)
Project startJune 15, 2021
Project endJune 30, 2025
Funding year2022
Award (this year)$1,050,471
NIH project number5R44HL145950-03
Project IDNIH-10429931 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients who require cardiac pacing and are suitable for leadless pacemaker implantation.

Less likely to help

Patients who do not require a pacemaker or those with specific contraindications for leadless devices may not benefit from this research.

What this research studies

This research focuses on developing a betavoltaic power source for leadless cardiac pacemakers (LCPs), which are innovative devices that do not require traditional leads. The goal is to create a battery that is significantly smaller and more powerful than current lithium-carbon batteries, allowing for longer-lasting and more versatile pacemakers. By achieving a battery size that is one-sixth of the current model and extending its lifespan to 20 years, this research aims to facilitate the use of dual and multi-chamber LCPs, which could benefit a larger population of patients with heart conditions. Patients may experience fewer surgeries and improved quality of life due to the enhanced technology.

Why it matters

Potential benefit: If successful, this research could provide patients with longer-lasting and more effective leadless pacemakers, reducing the need for multiple surgeries.

How similar studies have gone: Other research has shown promise in developing advanced battery technologies for medical devices, indicating potential success for this novel approach.

Where this research is happening

  • City Labs, INC.
    Miami, United States
    Active

Researchers

  • Principal investigator: Cabauy, Peter — City Labs, INC.
  • Study coordinator: Cabauy, Peter

Related research

Other NIH-funded projects on the same topics.

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  • Understanding how human heart pacemaker cells develop

    Scientists are studying how the human heart’s natural pacemaker forms, which could lead to better treatments for rhythm problems.

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  • Understanding how specialized heart pacemaker cells drive rhythm and dysfunction

    This NIH grant explores how distinct heart pacemaker cell subtypes contribute to normal rhythm and sinus node dysfunction, with the goal of guiding better treatments for heart rhythm problems.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11382758

  • Biopacemakers for aging hearts using stem-cell pacemaker cells

    Aims to help older patients with a faulty heart rhythm by using lab-made pacemaker cells grown from patients’ own stem cells.

    NIH research University of California at Davis · Davis, United States · NIH-11374738

  • Magnesium transporter and heart pacemaker: a primate model of arrhythmias

    A physician-scientist at Stanford is studying how a magnesium transporter affects the heart's natural pacemaker rhythm in primate-like models to better understand human arrhythmias.

    NIH research Stanford University · Stanford, United States · NIH-11372213

  • How heart pacemakers sense stretch and speed up

    A study at the University of Washington will explore how PIEZO channels in the heart’s pacemaker help the heart beat faster when the heart experiences stretch.

    NIH research University of Washington · Seattle, United States · NIH-11369783

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.