A new treatment to help regenerate dental pulp in children's teeth
Official title: Commercialization of the Vital-Dent Regenerative Pulp Therapy
Funded at Vic Foundry, INC. · NIH-10921494 · Data updated 2026-11-12
This study is testing a new gel called Vital-Dent that helps heal damaged teeth in kids by encouraging the growth of healthy tissue, making it easier for them to keep their teeth and avoid more complicated treatments.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vic Foundry, INC. NIH-funded |
| Lab location | 1 site (Fayetteville, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $1,434,831 |
| NIH project number | 1R44DE033313-01A1 |
| Project ID | NIH-10921494 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who have experienced dental injuries or severe decay affecting their teeth.
✕Less likely to help
Patients with fully developed adult teeth or those who do not have dental pulp damage may not benefit from this treatment.
What this research studies
This research focuses on developing a hydrogel treatment called Vital-Dent, which aims to regenerate vital pulp tissue in children's teeth that have been damaged due to injury or decay. The hydrogel is made from biopolymers and is designed to be placed in the tooth's pulp canal, where it promotes healing and helps maintain the tooth's vitality. By using this innovative approach, the treatment seeks to improve outcomes for pediatric patients who require endodontic procedures, potentially reducing the need for more invasive treatments. The study will evaluate the effectiveness of this hydrogel in promoting tooth retention and preventing future complications.
Why it matters
Potential benefit: If successful, this research could significantly improve dental health outcomes for children by preserving their teeth and reducing the need for more invasive procedures.
How similar studies have gone: While the approach of using hydrogels for dental pulp regeneration is innovative, there have been some preliminary successes in similar regenerative therapies, indicating potential for positive outcomes.
Where this research is happening
-
Vic Foundry, INC.
Fayetteville, United States Active
Researchers
- Principal investigator: Su, Xiaoli — Vic Foundry, INC.
- Study coordinator: Su, Xiaoli
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.