A new treatment for vaginal issues related to menopause

Regenerative biomaterial for combating genitourinary syndrome of menopause

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-11187044

This study is testing a new treatment using a special gel to help relieve dryness and discomfort for women going through menopause, aiming to make them feel more comfortable and improve their vaginal health.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded)
Locations1 site (LA JOLLA, UNITED STATES)
Trial IDNIH-11187044 on ClinicalTrials.gov

What this research studies

This research focuses on developing a novel regenerative therapy to address genitourinary syndrome of menopause (GSM), a condition affecting many perimenopausal and menopausal women. The approach involves using a tissue-derived hydrogel that can be applied topically to repair atrophic vaginal tissue, aiming to alleviate symptoms such as dryness, discomfort, and pain. The study will evaluate the effectiveness of this therapy in promoting cell growth and improving tissue health, providing a potentially safe and accessible option for women suffering from GSM.

Who could benefit from this research

Good fit: Ideal candidates for this research are perimenopausal and menopausal women suffering from genitourinary syndrome of menopause.

Not a fit: Patients who are not experiencing symptoms of genitourinary syndrome of menopause or who are not in the perimenopausal or menopausal stages may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a much-needed effective treatment option for women experiencing debilitating symptoms of menopause-related vaginal issues.

How similar studies have performed: Previous research has shown promise with similar regenerative therapies, indicating potential for success in this novel approach.

Where this research is happening

LA JOLLA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.