A new treatment for chronic wounds using a stable growth factor formulation
Official title: Hyperstable FGF1-FGF2 based therapeutic formulation for wound care
Funded at University of Arkansas at Fayetteville · NIH-10876032 · Data updated 2026-11-12
This study is testing a new treatment that combines two special proteins to help heal stubborn wounds better, especially for people with diabetes and heart issues, making it easier for them to recover and improve their quality of life.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arkansas at Fayetteville NIH-funded |
| Lab location | 1 site (Fayetteville, United States) |
| Project start | September 10, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $435,226 |
| NIH project number | 1R15GM154267-01 |
| Project ID | NIH-10876032 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients suffering from chronic wounds, particularly those with diabetes or cardiovascular conditions.
✕Less likely to help
Patients with acute wounds or those not suffering from chronic conditions related to wound healing may not benefit from this research.
What this research studies
This research focuses on developing a new therapeutic formulation that combines two growth factors, FGF1 and FGF2, to enhance the healing of chronic wounds, particularly in patients with diabetes and cardiovascular diseases. The approach aims to overcome common challenges in wound care, such as the instability of growth factors and the difficulty in delivering them effectively to the wound site. By creating a hyperstable version of these growth factors, the research seeks to improve healing outcomes and reduce the burden of chronic wounds on patients' quality of life. The effectiveness of this treatment will be monitored using advanced imaging techniques to ensure that it promotes healing effectively.
Why it matters
Potential benefit: If successful, this research could significantly improve the healing process for patients with chronic wounds, leading to better health outcomes and enhanced quality of life.
How similar studies have gone: Previous research has shown promise in using growth factors for wound healing, but this specific approach of creating a hyperstable formulation is novel.
Where this research is happening
-
University of Arkansas at Fayetteville
Fayetteville, United States Active
Researchers
- Principal investigator: Thallapuranam, Suresh Kumar Krishnaswamy — University of Arkansas at Fayetteville
- Study coordinator: Thallapuranam, Suresh Kumar Krishnaswamy
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.