A new tool to analyze how immune cells function and interact.
Official title: Dynamic single-cell analysis instrument to evaluate immune cell function
Funded at Cellchorus INC. · NIH-10835420 · Data updated 2026-11-12
This study is exploring a new way to watch and understand how immune cells behave and interact with each other, which could help create better treatments for diseases.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cellchorus INC. NIH-funded |
| Lab location | 1 site (Houston, UNITED STATES) |
| Project start | May 1, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $1,483,544 |
| NIH project number | 4R44GM149106-02 |
| Project ID | NIH-10835420 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that affect immune cell function, such as autoimmune diseases or cancers.
✕Less likely to help
Patients with stable, non-progressive conditions that do not involve immune cell dysfunction may not benefit from this research.
What this research studies
This research focuses on developing an innovative instrument that uses advanced imaging and artificial intelligence to analyze the behavior and interactions of immune cells at a single-cell level. By employing Time-lapse Imaging Microscopy in Nanowell Grids (TIMING™), the project aims to track and characterize the performance of thousands of individual cells, including disease cells and T-cells. This approach allows for a deeper understanding of cellular functions and interactions, which is crucial for developing new therapies and clinical biomarkers.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding immune responses and the development of more effective therapies for various diseases.
How similar studies have gone: Previous research has shown success with similar single-cell analysis techniques, indicating a promising avenue for advancing our understanding of cellular behavior.
Where this research is happening
-
Cellchorus INC.
Houston, United States Active
Researchers
- Principal investigator: Cooper, Laurence J.n. — Cellchorus INC.
- Study coordinator: Cooper, Laurence J.n.
Related research
Other NIH-funded projects on the same topics.
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LF-TIMING: Large-scale profiling of cell-cell interactions with label-free imaging
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A new instrument to understand how immune cells work
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TIMING: AI-powered single-cell analysis to improve cell therapies
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Dynamic single-cell analysis instrument ready to help labs map how individual cells behave
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Understanding how immune cells behave to improve cell therapies
This study is working on a new way to closely watch and understand immune cells used in treatments, so we can see how they behave and grow, helping doctors predict how well these therapies might work for patients before they start.
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Advanced Technology to Understand Immune Cell Behavior
This project is creating a new technology that uses advanced imaging and artificial intelligence to better understand how individual immune cells work and interact, which can help develop new treatments.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.