A new tool for quickly measuring a key protein to help detect pre-eclampsia in pregnant women.
Quantitative measurement of PlGF using a rapid, low-cost, point-of-care (POC) diagnostic platform for prediction and detection of pre-eclampsia
This study is working on a quick and easy test to check for a substance called Placental Growth Factor (PlGF) that helps predict pre-eclampsia in pregnant women, making it easier for doctors to spot and treat this serious condition early on.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ricovr Healthcare INC. NIH-funded |
| Lab location | 1 site (Princeton, United States) |
| Project ID | NIH-10820752 on NIH RePORTER |
What this research studies
This research focuses on developing a rapid and affordable diagnostic tool to measure Placental Growth Factor (PlGF), which is crucial for predicting and detecting pre-eclampsia, a serious condition affecting pregnant women. The innovative platform uses a plasmonic fiber-optic absorbance biosensor to provide quantitative results in as little as ten minutes without the need for complex procedures. By improving the accuracy and accessibility of pre-eclampsia diagnostics, this research aims to address disparities in maternal healthcare and enhance early detection and treatment options for at-risk women.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women, particularly those at higher risk for pre-eclampsia due to factors such as race or socioeconomic status.
Not a fit: Patients who are not pregnant or those who do not have risk factors for pre-eclampsia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of pre-eclampsia, potentially reducing maternal and infant morbidity and mortality.
How similar studies have performed: Previous research has shown promise in using biomarkers like PlGF for diagnosing pre-eclampsia, but this specific approach with a point-of-care device is novel.
Where this research is happening
Princeton, United States
- Ricovr Healthcare INC. — Princeton, United States (Active)
Researchers
- Principal investigator: Seimetz, Joseph — Ricovr Healthcare INC.
- Study coordinator: Seimetz, Joseph
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.