A new tool for quick examination of tissue samples without slides
Deep learning microscope for slide-free and digital histology
This study is testing a new tool that uses advanced technology to quickly analyze tissue samples right where patients are treated, making it easier for doctors to check for cancer in the mouth and improve care for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rice University NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11061920 on NIH RePORTER |
What this research studies
This research focuses on developing an innovative tool that utilizes deep learning and advanced optical techniques to analyze fresh tissue samples directly at the point of care. By eliminating the need for traditional slide preparation, this approach aims to make histopathological assessments faster and more accessible, particularly in resource-limited settings. The tool will be validated for assessing tumor margins in patients with oral squamous cell carcinoma, which is crucial for effective cancer treatment. The project seeks to enhance diagnostic capabilities and improve patient outcomes by integrating artificial intelligence into the analysis process.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients undergoing surgery for oral squamous cell carcinoma.
Not a fit: Patients with conditions that do not involve tissue resection or those not diagnosed with oral squamous cell carcinoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the speed and accuracy of cancer diagnoses, leading to better treatment outcomes for patients.
How similar studies have performed: Other research has shown promising results using AI and advanced imaging techniques in pathology, indicating potential success for this novel approach.
Where this research is happening
Houston, United States
- Rice University — Houston, United States (Active)
Researchers
- Principal investigator: Richards-Kortum, Rebecca R. — Rice University
- Study coordinator: Richards-Kortum, Rebecca R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.