A new tool for diagnosing eosinophilic esophagitis in children
Dual-wavelength endoscopic Raman probe for eosinophilic esophagitis
['FUNDING_R01'] · VANDERBILT UNIVERSITY · NIH-11127494
This study is testing a new tool that uses light to help doctors quickly and accurately diagnose eosinophilic esophagitis (EoE) in kids, making it easier for them to get the right care without needing lots of tissue samples.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VANDERBILT UNIVERSITY (nih funded) |
| Locations | 1 site (Nashville, UNITED STATES) |
| Trial ID | NIH-11127494 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a dual-wavelength endoscopic Raman probe to improve the diagnosis of eosinophilic esophagitis (EoE) in children. EoE is a chronic inflammatory condition that can cause significant feeding and swallowing difficulties. The study aims to utilize Raman spectroscopy, a technique that analyzes the biochemical composition of tissues, to provide real-time diagnostic information during endoscopic procedures. By doing so, it seeks to reduce the reliance on multiple biopsies and enhance the accuracy of EoE diagnosis.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who are experiencing symptoms related to eosinophilic esophagitis.
Not a fit: Patients who do not have eosinophilic esophagitis or are older than 11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnoses of eosinophilic esophagitis, improving treatment outcomes for affected children.
How similar studies have performed: Previous research has shown promise in using Raman spectroscopy for diagnostic purposes, indicating potential success for this novel approach.
Where this research is happening
Nashville, UNITED STATES
- VANDERBILT UNIVERSITY — Nashville, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MAHADEVAN-JANSEN, ANITA — VANDERBILT UNIVERSITY
- Study coordinator: MAHADEVAN-JANSEN, ANITA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.