A new tool for better early detection of melanoma

Fast, large area, multiphoton exoscope (FLAME) for improving early detection of melanoma

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-10914116

This study is testing a new imaging tool called FLAME that helps doctors spot melanoma, a serious skin cancer, more accurately and quickly, so patients can get better care without unnecessary procedures.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA-IRVINE (nih funded)
Locations1 site (IRVINE, UNITED STATES)
Trial IDNIH-10914116 on ClinicalTrials.gov

What this research studies

This research focuses on developing a fast, large area multiphoton exoscope (FLAME) to improve the early detection of melanoma, a serious skin cancer. By using advanced imaging technology, the FLAME aims to provide more accurate, non-invasive assessments of skin lesions compared to traditional dermoscopy, which can often lead to false negatives. The goal is to enhance diagnostic accuracy, reduce unnecessary biopsies, and ultimately improve patient outcomes. The research will involve clinical evaluations to assess the effectiveness of this new imaging tool in real-world settings.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with suspicious skin lesions that may be melanoma or other melanocytic neoplasms.

Not a fit: Patients with confirmed melanoma or those without any skin lesions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier and more accurate detection of melanoma, improving survival rates and reducing treatment costs for patients.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for skin cancer detection, suggesting that this approach may lead to significant advancements in melanoma diagnosis.

Where this research is happening

IRVINE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.