A new test to quickly predict sepsis in patients
PredictSEP: A Predictive Diagnostic Assay for Sepsis
This study is working on a quick test that can help doctors predict how sepsis, a serious infection-related condition, might develop in patients by looking at certain white blood cells, so they can provide better care faster.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cfd Research Corporation NIH-funded |
| Lab location | 1 site (Huntsville, United States) |
| Project ID | NIH-10484762 on NIH RePORTER |
What this research studies
This research aims to develop a rapid diagnostic assay that can predict the onset and progression of sepsis, a life-threatening condition caused by the body's response to infection. By utilizing a microfluidics-based approach, the assay will analyze neutrophil behavior in patients to generate a predictive score that reflects their prognosis. The initial phase will validate the assay's effectiveness within 60 minutes using samples from sepsis patients, while the second phase will focus on creating the necessary instrumentation and conducting larger studies for FDA approval.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients diagnosed with sepsis, those with Systemic Inflammatory Response Syndrome (SIRS), and healthy individuals for comparison.
Not a fit: Patients who are not experiencing symptoms of infection or those with chronic conditions unrelated to sepsis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnosis of sepsis, potentially saving lives through timely treatment.
How similar studies have performed: Previous research has shown promise in developing rapid diagnostic assays for sepsis, but this specific approach utilizing neutrophil behavior is novel.
Where this research is happening
Huntsville, United States
- Cfd Research Corporation — Huntsville, United States (Active)
Researchers
- Principal investigator: Bhatt, Ketan H — Cfd Research Corporation
- Study coordinator: Bhatt, Ketan H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.