A new test to predict vascular diseases using kidney cell markers in urine
Podocyturia based assay as a predictive biomarker for systemic vascular diseases
['FUNDING_SBIR_1'] · TEUCER BIOTECH, INC. · NIH-11065195
This study is looking at a new way to spot early signs of heart problems by checking for special kidney cells in your urine, which could help doctors catch issues before you even feel symptoms, making it easier to take action early.
Quick facts
| Phase | ['FUNDING_SBIR_1'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TEUCER BIOTECH, INC. (nih funded) |
| Locations | 1 site (MIAMI, UNITED STATES) |
| Trial ID | NIH-11065195 on ClinicalTrials.gov |
What this research studies
This research investigates a novel biomarker called podocyturia, which involves the detection of specialized kidney cells in urine. By analyzing these cells, researchers aim to identify early signs of cardiovascular disease (CVD) before symptoms appear, such as hypertension or heart attacks. The approach focuses on the relationship between kidney cell injury and vascular health, potentially providing a more accurate prediction of CVD risk compared to traditional methods like measuring albumin levels. Patients will be monitored for podocyte shedding, which occurs without the complications of albumin reabsorption, allowing for earlier intervention.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for cardiovascular diseases, particularly those with conditions like diabetes or hypertension.
Not a fit: Patients who do not have risk factors for cardiovascular diseases or those with established CVD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and prevention of cardiovascular diseases, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using urinary biomarkers for early detection of vascular diseases, suggesting that this approach could be effective.
Where this research is happening
MIAMI, UNITED STATES
- TEUCER BIOTECH, INC. — MIAMI, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BADR, KAMAL — TEUCER BIOTECH, INC.
- Study coordinator: BADR, KAMAL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: adult onset diabetes, Adult-Onset Diabetes Mellitus