A new test to monitor how well patients are sticking to their HIV prevention medication.
A novel REverSe Transcriptase Chain Termination (RESTRICT) assay for near-patient, objective monitoring of long-term PrEP adherence
This study is testing a new way to check if people are taking their HIV prevention medication regularly by looking at blood samples, so doctors can get a clearer picture of how well the treatment is working for their patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10980562 on NIH RePORTER |
What this research studies
This research focuses on improving the monitoring of adherence to pre-exposure prophylaxis (PrEP) for HIV prevention. It aims to develop a novel assay called the RESTRICT assay, which measures drug levels in patients more accurately than traditional self-reports. By analyzing blood samples for long-term drug metabolites, the study seeks to provide healthcare providers with reliable data on patient adherence. The research will also evaluate how acceptable and feasible this new testing method is for both patients and providers in clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 21 and older who are using or considering using PrEP for HIV prevention.
Not a fit: Patients who are not using PrEP or are under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better monitoring of PrEP adherence, ultimately improving HIV prevention efforts.
How similar studies have performed: Other research has shown promise in developing objective adherence monitoring tools for PrEP, making this approach a potentially significant advancement.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Drain, Paul K — University of Washington
- Study coordinator: Drain, Paul K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.