A new test to detect liver cancer early using tiny particles from cells.
Official title: Developing and Automating an Extracellular Vesicle-Based Test for Early Detection of Hepatocellular Carcinoma
Funded at Eximius Diagnostics Corp · NIH-10929539 · Data updated 2026-11-12
This study is working on a new blood test that looks for tiny particles from your cells to help spot liver cancer early, so people can get the care they need sooner.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Eximius Diagnostics Corp NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 14, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $661,609 |
| NIH project number | 5R44CA288163-02 |
| Project ID | NIH-10929539 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at high risk for liver cancer, such as those with liver cirrhosis or chronic hepatitis B infection.
✕Less likely to help
Patients without liver disease or those who are not at risk for hepatocellular carcinoma may not benefit from this research.
What this research studies
This research focuses on developing a test that uses extracellular vesicles (tiny particles released by cells) to detect hepatocellular carcinoma (HCC), a common type of liver cancer, at an early stage. Current methods for detecting HCC are not very accurate, often missing early signs of the disease. The researchers aim to identify specific proteins on the surface of these vesicles that can indicate the presence of HCC, potentially leading to earlier and more reliable diagnoses. By analyzing blood samples, the test could provide crucial information about the disease before it progresses to a more severe stage.
Why it matters
Potential benefit: If successful, this research could lead to a more accurate and earlier detection of liver cancer, improving treatment outcomes for patients.
How similar studies have gone: Previous research has shown promise in using extracellular vesicles for cancer detection, indicating that this approach may be viable and beneficial.
Where this research is happening
-
Eximius Diagnostics Corp
Los Angeles, United States Active
Researchers
- Principal investigator: Tseng, Hsian-Rong — Eximius Diagnostics Corp
- Study coordinator: Tseng, Hsian-Rong
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.