A new test to detect liver cancer early using tiny particles from cells.

Developing and Automating an Extracellular Vesicle-Based Test for Early Detection of Hepatocellular Carcinoma

NIH-funded research Eximius Diagnostics Corp · NIH-10929539

This study is working on a new blood test that looks for tiny particles from your cells to help spot liver cancer early, so people can get the care they need sooner.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionEximius Diagnostics Corp NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-10929539 on NIH RePORTER

What this research studies

This research focuses on developing a test that uses extracellular vesicles (tiny particles released by cells) to detect hepatocellular carcinoma (HCC), a common type of liver cancer, at an early stage. Current methods for detecting HCC are not very accurate, often missing early signs of the disease. The researchers aim to identify specific proteins on the surface of these vesicles that can indicate the presence of HCC, potentially leading to earlier and more reliable diagnoses. By analyzing blood samples, the test could provide crucial information about the disease before it progresses to a more severe stage.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at high risk for liver cancer, such as those with liver cirrhosis or chronic hepatitis B infection.

Not a fit: Patients without liver disease or those who are not at risk for hepatocellular carcinoma may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a more accurate and earlier detection of liver cancer, improving treatment outcomes for patients.

How similar studies have performed: Previous research has shown promise in using extracellular vesicles for cancer detection, indicating that this approach may be viable and beneficial.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alcoholic Liver Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.