A new test for quickly identifying pathogens in endocarditis from blood samples
Commercialization Readiness Pilot (CRP) program support for: Direct-from-specimen identification of pathogens common in endocarditis
This study is testing a new, quick test that can find germs causing infective endocarditis in your blood in just three hours, helping doctors give you the right treatment faster and more accurately than traditional methods.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Helixbind, INC. NIH-funded |
| Lab location | 1 site (Boxborough, UNITED STATES) |
| Project ID | NIH-11094049 on NIH RePORTER |
What this research studies
This research focuses on developing a rapid diagnostic test called RaPID/IE that can identify and characterize pathogens causing infective endocarditis directly from blood samples in about three hours. Unlike traditional methods that rely on blood cultures, which can take longer and may yield false negatives, this automated test provides faster and more accurate results. It is designed to detect both bacterial and fungal pathogens and includes a marker for antimicrobial resistance, ensuring that patients receive the most effective treatment promptly.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients suspected of having infective endocarditis, particularly those who may benefit from rapid diagnosis and targeted antimicrobial therapy.
Not a fit: Patients who do not have infective endocarditis or those who are not experiencing symptoms related to this condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the time to diagnosis and improve treatment outcomes for patients with infective endocarditis.
How similar studies have performed: Other research has shown promise in developing rapid diagnostic tests for infectious diseases, indicating that this approach has potential for success.
Where this research is happening
Boxborough, UNITED STATES
- Helixbind, INC. — Boxborough, United States (Active)
Researchers
- Principal investigator: Singer, Alon — Helixbind, INC.
- Study coordinator: Singer, Alon
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.