A new test for quickly detecting Ebola virus infection in the field
A Fully Integrated Point-of-Care Test for Ebola
This study is working on a quick and easy test called the D4 assay that can help doctors find out if someone has Ebola in just 30 minutes, making it easier to get patients the treatment they need sooner.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10911226 on NIH RePORTER |
What this research studies
This research aims to develop a point-of-care test called the D4 assay for the early detection of Ebola virus infection. Unlike traditional methods that require complex laboratory setups and trained personnel, the D4 assay is designed to be simple and quick, providing results in just 30 minutes. It utilizes customized monoclonal antibodies to detect a specific viral glycoprotein present in the blood of infected individuals, allowing for earlier diagnosis than current methods. This could enable timely treatment and improve survival rates for patients with low levels of the virus.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suspected of having Ebola virus infection, particularly in outbreak settings.
Not a fit: Patients who are not at risk of Ebola virus infection or those already diagnosed and receiving treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the speed and reliability of Ebola virus diagnosis, leading to better patient outcomes.
How similar studies have performed: Previous research has shown promise in developing rapid diagnostic tests for infectious diseases, indicating potential success for this novel approach.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Chilkoti, Ashutosh — Duke University
- Study coordinator: Chilkoti, Ashutosh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.