A new test for Lyme disease that simplifies diagnosis
Hybrid ELISA: Simple and specific one-tier assay for Lyme disease
This study is working on a new test for Lyme disease that will make it faster and easier to get an accurate diagnosis, helping patients with symptoms get the right treatment sooner and avoid unnecessary antibiotics.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kephera Diagnostics, LLC NIH-funded |
| Lab location | 1 site (Framingham, UNITED STATES) |
| Project ID | NIH-10927442 on NIH RePORTER |
What this research studies
This research focuses on developing a hybrid ELISA test for Lyme disease, which aims to streamline the current two-step testing protocol that often leads to delays in diagnosis and treatment. By improving the specificity of the assay, the goal is to reduce false positives and unnecessary antibiotic prescriptions. Patients who exhibit symptoms of Lyme disease will benefit from a quicker and more accurate diagnosis, potentially leading to timely treatment. The methodology involves advanced immunochemical techniques to enhance the detection of specific antigens related to Borrelia burgdorferi.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals exhibiting symptoms of Lyme disease or those who have been exposed to ticks in endemic areas.
Not a fit: Patients who have already been diagnosed with Lyme disease and are receiving treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnoses of Lyme disease, reducing unnecessary antibiotic use.
How similar studies have performed: Previous research has shown promise in improving diagnostic assays for infectious diseases, indicating that this approach could yield significant advancements.
Where this research is happening
Framingham, UNITED STATES
- Kephera Diagnostics, LLC — Framingham, United States (Active)
Researchers
- Principal investigator: Levin, Andrew E. — Kephera Diagnostics, LLC
- Study coordinator: Levin, Andrew E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.