A new test for diagnosing invasive fungal infections
Multiplexed rapid immunoassay for invasive fungal disease
This study is working on a quick and easy test to help doctors find serious fungal infections in patients, like those getting chemotherapy or organ transplants, so they can start treatment sooner and improve health outcomes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nevada Reno NIH-funded |
| Lab location | 1 site (Reno, United States) |
| Project ID | NIH-10691231 on NIH RePORTER |
What this research studies
This research focuses on developing a rapid immunoassay to diagnose invasive fungal diseases, which are a significant risk for patients undergoing treatments like chemotherapy or organ transplants. The test will analyze serum, plasma, or urine samples to detect specific fungal components, allowing for early identification of infections caused by fungi such as Aspergillus and Candida. By using monoclonal antibodies that target unique fungal markers, the goal is to create a user-friendly and cost-effective diagnostic tool suitable for primary healthcare settings. This approach aims to improve patient outcomes through timely and accurate diagnosis.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients undergoing immunosuppressive treatments, such as those with cancer or those who have received organ transplants.
Not a fit: Patients who are not at high risk for invasive fungal infections, such as those with healthy immune systems, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnoses of invasive fungal infections, improving treatment outcomes for at-risk patients.
How similar studies have performed: Other research has shown promise in developing similar diagnostic tests for fungal infections, indicating that this approach has potential for success.
Where this research is happening
Reno, United States
- University of Nevada Reno — Reno, United States (Active)
Researchers
- Principal investigator: Kozel, Thomas R — University of Nevada Reno
- Study coordinator: Kozel, Thomas R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.