A new technology to analyze proteins in cancer tissues
An integrated microtechnology platform for spatially resolved mass spectrometry-based proteomics
['FUNDING_R01'] · STANFORD UNIVERSITY · NIH-11010802
This study is working on a new technology to closely examine proteins in cancer tissues, which could help doctors better understand how cancer develops and responds to treatments, leading to better tests and personalized care for patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-11010802 on ClinicalTrials.gov |
What this research studies
This research focuses on developing an advanced microtechnology platform that allows for detailed analysis of proteins in biological tissues, particularly in the context of cancer. By utilizing a method that combines tissue dissection with mass spectrometry, the project aims to achieve high-resolution mapping of protein abundance and their spatial distribution. This approach is crucial for understanding how proteins influence cancer initiation, progression, and response to treatment, ultimately aiding in the identification of biomarkers and therapeutic targets. Patients may benefit from improved diagnostic tools and personalized treatment strategies based on the findings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with various types of cancer, particularly those with cutaneous squamous cell carcinoma.
Not a fit: Patients with non-cancerous conditions or those not undergoing treatment for cancer may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate cancer diagnostics and targeted therapies, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using mass spectrometry for protein analysis, but this integrated approach is relatively novel and aims to enhance the depth of proteomic coverage significantly.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TANG, SINDY KAM-YAN — STANFORD UNIVERSITY
- Study coordinator: TANG, SINDY KAM-YAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Biology, cancer initiation, cancer metastasis, cancer microenvironment, cancer progression