A new technology to analyze proteins in cancer tissues
Official title: An integrated microtechnology platform for spatially resolved mass spectrometry-based proteomics
Funded at Stanford University · NIH-11010802 · Data updated 2026-11-12
This study is working on a new technology to closely examine proteins in cancer tissues, which could help doctors better understand how cancer develops and responds to treatments, leading to better tests and personalized care for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | January 6, 2023 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $611,702 |
| NIH project number | 5R01CA283247-03 |
| Project ID | NIH-11010802 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with various types of cancer, particularly those with cutaneous squamous cell carcinoma.
✕Less likely to help
Patients with non-cancerous conditions or those not undergoing treatment for cancer may not receive any benefit from this research.
What this research studies
This research focuses on developing an advanced microtechnology platform that allows for detailed analysis of proteins in biological tissues, particularly in the context of cancer. By utilizing a method that combines tissue dissection with mass spectrometry, the project aims to achieve high-resolution mapping of protein abundance and their spatial distribution. This approach is crucial for understanding how proteins influence cancer initiation, progression, and response to treatment, ultimately aiding in the identification of biomarkers and therapeutic targets. Patients may benefit from improved diagnostic tools and personalized treatment strategies based on the findings.
Why it matters
Potential benefit: If successful, this research could lead to more accurate cancer diagnostics and targeted therapies, improving patient outcomes.
How similar studies have gone: Previous research has shown promise in using mass spectrometry for protein analysis, but this integrated approach is relatively novel and aims to enhance the depth of proteomic coverage significantly.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Tang, Sindy Kam-Yan — Stanford University
- Study coordinator: Tang, Sindy Kam-Yan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.