A new targeted antibody treatment for ovarian cancer

A novel targeted antibody therapeutic to treat ovarian cancer

['FUNDING_SBIR_1'] · TRIO PHARMACEUTICALS INC. · NIH-10820095

This study is testing a new treatment for ovarian cancer that helps your immune system fight the disease better by targeting harmful cells in the tumor, and it's designed for women who haven't had success with regular chemotherapy.

Quick facts

Phase['FUNDING_SBIR_1']
Study typeNih_funding
SexAll
SponsorTRIO PHARMACEUTICALS INC. (nih funded)
Locations1 site (MURRIETA, UNITED STATES)
Trial IDNIH-10820095 on ClinicalTrials.gov

What this research studies

This research focuses on developing a targeted antibody therapeutic specifically designed to treat ovarian cancer, which is a leading cause of cancer deaths among women. The approach aims to enhance the immune system's ability to fight tumors by selectively targeting and eliminating immunosuppressive cells in the tumor microenvironment, while also attacking cancer cells. By addressing the limitations of current immuno-oncology drugs, this research seeks to provide a more effective treatment option for patients who have not responded well to traditional chemotherapy. The study will involve clinical trials to evaluate the safety and efficacy of this novel therapeutic.

Who could benefit from this research

Good fit: Ideal candidates for this research are women diagnosed with ovarian cancer who have not responded adequately to existing chemotherapy treatments.

Not a fit: Patients with early-stage ovarian cancer or those who have not yet undergone chemotherapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a more effective treatment for ovarian cancer, potentially improving survival rates and quality of life for patients.

How similar studies have performed: While immuno-oncology approaches have shown promise in other cancers, this specific targeted antibody therapeutic represents a novel approach that has not yet been tested in clinical settings for ovarian cancer.

Where this research is happening

MURRIETA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Anti-Cancer Agents, Cancer Drug, Neoplastic Disease Chemotherapeutic Agents, anti-cancer drug, Cancers

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.