A new system to measure heart cell electrical activity quickly and efficiently
Official title: An in vitro electrophysiology system for high-throughput measurement of cardiomyocyte action potential
Funded at Cyion Technologies, LLC · NIH-10759677 · Data updated 2026-11-12
This study is working on a new, easier way to measure how heart cells behave electrically, which could help researchers better understand heart diseases and find new treatments, even if they don’t have a lot of experience in this area.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cyion Technologies, LLC NIH-funded |
| Lab location | 1 site (Pleasanton, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $343,203 |
| NIH project number | 1R43HL170918-01 |
| Project ID | NIH-10759677 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with heart diseases or conditions that affect cardiac function.
✕Less likely to help
Patients with non-cardiac related health issues or those who do not have any cardiovascular conditions may not benefit from this research.
What this research studies
This research focuses on developing an innovative in vitro electrophysiology system designed to measure the electrical activity of heart cells, known as cardiomyocytes, at a high throughput. By utilizing a novel 3D nanoelectrode array, the system aims to simplify the process of recording intracellular action potentials, making it accessible even to researchers with limited expertise in electrophysiology. The goal is to create a reliable and scalable method for assessing cardiac function, which is crucial for understanding heart diseases and developing new therapies. This approach addresses the limitations of current measurement techniques, which are often complex and costly.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for diagnosing and treating heart diseases, ultimately saving lives.
How similar studies have gone: While the approach is innovative, similar high-throughput electrophysiology techniques have shown promise in other contexts, indicating potential for success.
Where this research is happening
-
Cyion Technologies, LLC
Pleasanton, United States Active
Researchers
- Principal investigator: Jiang, Xin — Cyion Technologies, LLC
- Study coordinator: Jiang, Xin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.