A new system for detecting disease-related microRNA biomarkers in blood samples
Integrated Acoustofluidic Plasmonic Molecular Diagnostic System for Detecting MicroRNA Biomarkers
['FUNDING_R01'] · DUKE UNIVERSITY · NIH-10542811
This study is working on a new way to quickly find tiny markers in your blood that can help doctors spot diseases like cancer and heart problems early on, using some cool technology to make the process easier and more accurate for everyone.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DUKE UNIVERSITY (nih funded) |
| Locations | 1 site (DURHAM, UNITED STATES) |
| Trial ID | NIH-10542811 on ClinicalTrials.gov |
What this research studies
This research aims to create a diagnostic system that can quickly isolate and identify microRNA biomarkers found in exosomes from blood samples. These biomarkers are important for early detection of various diseases, including cancer and cardiovascular conditions. The project utilizes advanced technologies, including acoustofluidic methods for exosome isolation and surface-enhanced Raman scattering for detection, to improve the accuracy and efficiency of diagnosis. By addressing the technical challenges of current methods, this research seeks to make these diagnostic tools more accessible for clinical use.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for diseases such as cancer or cardiovascular conditions who may benefit from early detection.
Not a fit: Patients with conditions that do not involve dysregulated microRNA biomarkers may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of diseases, improving patient outcomes.
How similar studies have performed: Other research has shown promise in using microRNA biomarkers for disease detection, but this specific integrated approach is relatively novel.
Where this research is happening
DURHAM, UNITED STATES
- DUKE UNIVERSITY — DURHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: VO-DINH, TUAN — DUKE UNIVERSITY
- Study coordinator: VO-DINH, TUAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Infection