A new system for analyzing tiny particles that help cells communicate.
Official title: STEADI:System for Translational Exosome Analysis and Diagnostics through Integrating electroporation and single-molecule detection
Funded at Johns Hopkins University · NIH-11055432 · Data updated 2026-11-12
This study is testing a new system called STEADI that helps scientists better understand tiny particles called extracellular vesicles, which are important for cell communication and can help diagnose diseases, making it easier for doctors to use this information in both research and patient care.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | March 15, 2024 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $207,365 |
| NIH project number | 5R21TR005063-02 |
| Project ID | NIH-11055432 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that can be diagnosed through the analysis of extracellular vesicles.
✕Less likely to help
Patients who do not have conditions related to cell communication or extracellular vesicle involvement may not benefit from this research.
What this research studies
This research focuses on developing a novel system called STEADI, which aims to improve the analysis of extracellular vesicles (EVs) that play a vital role in cell communication and can serve as diagnostic markers for diseases. By integrating advanced techniques like microfluidic electroporation and single-molecule detection, STEADI will allow for precise sorting and detailed analysis of EVs based on their surface profiles. This innovative approach seeks to enhance the reliability and efficiency of EV analysis, making it more applicable in both research and clinical settings.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnostic tools for complex diseases, improving patient outcomes.
How similar studies have gone: Other research has shown promise in using similar techniques for analyzing extracellular vesicles, indicating potential for success in this approach.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Hur, Soojung Claire — Johns Hopkins University
- Study coordinator: Hur, Soojung Claire
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.