A new stent to keep a vital blood vessel open in newborns with heart defects
DUCTUS ARTERIOSUS STENT TO IMPROVE CONGENITAL HEART DEFECT MORTALITY
This study is testing a new stent designed just for newborns with heart issues to help keep an important blood vessel open, making it safer and easier for doctors to treat these tiny patients without needing more surgeries.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Starlight Cardiovascular, INC. NIH-funded |
| Lab location | 1 site (San Diego, UNITED STATES) |
| Project ID | NIH-11044511 on NIH RePORTER |
What this research studies
This research focuses on developing a specialized stent for the ductus arteriosus, a crucial blood vessel in newborns that typically closes after birth. The stent is designed to address the unique anatomical challenges faced by pediatric cardiovascular physicians, who currently use adult devices that are not suitable for infants. By creating a stent specifically for this purpose, the research aims to reduce the need for reinterventions and the risks associated with open-heart surgery in neonates with congenital heart defects. The study involves testing the stent's feasibility and effectiveness in maintaining ductus patency, which is essential for the survival of affected newborns.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns with congenital heart defects that necessitate the maintenance of ductus arteriosus patency.
Not a fit: Patients who do not have congenital heart defects or are older than the neonatal age group may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly lower the risks of morbidity and mortality in newborns with congenital heart defects requiring ductus arteriosus patency.
How similar studies have performed: While there have been efforts to adapt adult stents for pediatric use, this approach is novel as it specifically designs a stent for the unique needs of newborns with congenital heart defects.
Where this research is happening
San Diego, UNITED STATES
- Starlight Cardiovascular, INC. — San Diego, United States (Active)
Researchers
- Principal investigator: Tang, Beverly — Starlight Cardiovascular, INC.
- Study coordinator: Tang, Beverly
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.