A new sensor to detect RNA biomarkers in saliva and serum.
Official title: Multiplex Hybridization Colorimetric Sensor for Wild Type and Variant RNA Biomarkers
Funded at Oklahoma State University Stillwater · NIH-10580293 · Data updated 2026-11-12
This study is working on a new, easy-to-use test that can quickly check for several important RNA markers in your saliva and blood, making it simpler and cheaper to diagnose diseases early, especially in places that might not have fancy lab equipment.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oklahoma State University Stillwater NIH-funded |
| Lab location | 1 site (Stillwater, United States) |
| Project start | July 11, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2023 |
| Award (this year) | $438,878 |
| NIH project number | 1R15EB034037-01 |
| Project ID | NIH-10580293 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who require diagnostic testing for viral infections or other conditions detectable through RNA biomarkers.
✕Less likely to help
Patients with conditions that do not involve RNA biomarkers or those who do not require diagnostic testing may not benefit from this research.
What this research studies
This research focuses on developing a colorimetric sensor that can detect multiple RNA biomarkers simultaneously in saliva and serum samples. Unlike traditional methods like RT-PCR, which require expensive equipment and highly trained personnel, this sensor aims to provide a more accessible and affordable diagnostic tool. By using a multiplex approach, the sensor will enhance detection capabilities and reduce the chances of false negatives, making it suitable for resource-limited settings. The goal is to facilitate early diagnosis and monitoring of diseases, particularly in the context of ongoing health crises.
Why it matters
Potential benefit: If successful, this research could lead to more accessible and accurate diagnostic tools for detecting viral infections and other disorders.
How similar studies have gone: Other research has shown promise in developing colorimetric sensors for diagnostics, but this multiplex approach is relatively novel.
Where this research is happening
-
Oklahoma State University Stillwater
Stillwater, United States Active
Researchers
- Principal investigator: Krishnan, Sadagopan — Oklahoma State University Stillwater
- Study coordinator: Krishnan, Sadagopan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.