A new self-testing method for early HIV detection using CRISPR technology
Official title: A rapid CRISPR-based self-testing platform for early detection of HIV
Funded at University of Florida · NIH-11013398 · Data updated 2026-11-12
This study is working on a quick and easy way for people to test themselves for HIV at home using advanced CRISPR technology, so they can get results in about 30 minutes and take action sooner if needed.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | January 19, 2024 |
| Project end | December 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $409,335 |
| NIH project number | 5R61AI181016-02 |
| Project ID | NIH-11013398 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk of HIV infection or those who may have been exposed to the virus.
✕Less likely to help
Patients who are already diagnosed with HIV or those who do not have risk factors for HIV infection may not benefit from this research.
What this research studies
This research focuses on developing a rapid and automated self-testing platform that utilizes CRISPR technology for the early detection of HIV. By leveraging engineered CRISPR/Cas systems, the platform aims to identify HIV RNA quickly and accurately, allowing individuals to test themselves without the need for extensive laboratory procedures. The method is designed to provide results in about 30 minutes, significantly improving the chances of early intervention and reducing the risk of transmission. The approach is based on innovative techniques that enhance the sensitivity and specificity of the tests.
Why it matters
Potential benefit: If successful, this research could lead to a highly accessible and efficient method for early HIV detection, potentially saving lives and reducing transmission rates.
How similar studies have gone: Other research has shown promising results with CRISPR-based diagnostic methods, indicating that this approach could be effective for HIV detection as well.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Jain, Piyush K — University of Florida
- Study coordinator: Jain, Piyush K
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.