A new scoring system to evaluate lung transplant candidates

An Automated Frailty Scoring System for Lung Transplantation Based on Bio-Geo-Composition

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-11170712

This study is working on a new tool to help doctors better understand how fit someone is for a lung transplant by looking at their chest scans, which could lead to better outcomes for patients like you.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-11170712 on NIH RePORTER

What this research studies

This research aims to develop an automated scoring system called the Pittsburgh Transplant Fitness Score (PTFS) to assess the fitness of candidates for lung transplantation. By analyzing pre-transplant chest CT scans, the study will evaluate biological and geometric factors that may influence transplant outcomes. The approach utilizes advanced algorithms to quantify these factors, which could lead to better patient selection and improved survival rates after lung transplants. The goal is to enhance the understanding of how individual characteristics impact the success of lung transplants.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from end-stage lung diseases who are being considered for lung transplantation.

Not a fit: Patients who are not candidates for lung transplantation or those with conditions unrelated to lung health may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved outcomes and survival rates for lung transplant patients.

How similar studies have performed: Other research has shown promise in using automated scoring systems for patient selection in organ transplantation, suggesting that this approach could be effective.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.