A new scanner to measure oxygen levels in tumors for better cancer treatment
Official title: EPR scanner for tumor oximetry in the clinic
Funded at Dartmouth College · NIH-11210724 · Data updated 2026-11-12
This study is working on a new, easy-to-use scanner that checks how much oxygen is in tumors for cancer patients, helping doctors give the best timing and treatment for radiotherapy to improve results.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $120,999 |
| NIH project number | 3R01CA269234-03S1 |
| Project ID | NIH-11210724 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are cancer patients undergoing radiotherapy who require monitoring of tumor oxygen levels.
✕Less likely to help
Patients who are not undergoing cancer treatment or those with tumors that do not require oxygen level monitoring may not benefit from this research.
What this research studies
This research aims to develop a user-friendly clinical scanner that measures tumor oxygen levels in real-time for cancer patients. By providing accurate and immediate data on tumor oxygenation, the scanner will help healthcare providers optimize the timing and delivery of radiotherapy, potentially enhancing treatment effectiveness. The project combines expertise from academia and industry to create a reliable medical device that can be used in various clinical settings. The research team has previously demonstrated the safety and feasibility of this technology in clinical trials.
Why it matters
Potential benefit: If successful, this research could lead to improved cancer treatment outcomes by allowing for more precise radiotherapy planning.
How similar studies have gone: Previous studies have shown the feasibility and safety of EPR oximetry in clinical settings, indicating a promising foundation for this research.
Where this research is happening
-
Dartmouth College
Hanover, United States Active
Researchers
- Principal investigator: Kuppusamy, Periannan — Dartmouth College
- Study coordinator: Kuppusamy, Periannan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.