A new scanner to measure oxygen levels in tumors for better cancer treatment
Official title: EPR scanner for tumor oximetry in the clinic
Funded at Dartmouth College · NIH-10992613 · Data updated 2026-11-12
This study is working on a new, easy-to-use scanner that checks oxygen levels in cancer tumors, helping doctors give the best timing and treatment for radiotherapy to improve care for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $645,050 |
| NIH project number | 5R01CA269234-03 |
| Project ID | NIH-10992613 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are cancer patients undergoing radiotherapy who require precise tumor oxygen measurements.
✕Less likely to help
Patients who are not undergoing radiotherapy or those with non-cancerous conditions may not benefit from this research.
What this research studies
This research aims to develop a user-friendly clinical scanner that measures oxygen levels in tumors of cancer patients. By providing real-time data on tumor oxygenation, the scanner will help healthcare providers optimize the timing and delivery of radiotherapy, potentially enhancing treatment effectiveness. The project involves collaboration between academic researchers and a medical device company to ensure the scanner is practical for everyday clinical use. The technology builds on previous successful demonstrations of safety and feasibility in measuring tumor oxygen levels.
Why it matters
Potential benefit: If successful, this research could lead to improved cancer treatment outcomes through more effective radiotherapy planning.
How similar studies have gone: Previous studies have shown the feasibility and safety of EPR oximetry in clinical settings, indicating a promising foundation for this new scanner.
Where this research is happening
-
Dartmouth College
Hanover, United States Active
Researchers
- Principal investigator: Kuppusamy, Periannan — Dartmouth College
- Study coordinator: Kuppusamy, Periannan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.