A new prosthetic device to treat severe ankle and hindfoot damage

A COMPLIANT ANKLE ENDOPROSTHESIS TO TREAT ANKLE-HINDFOOT PATHOLOGY

NIH-funded research Flex Orthopaedics, INC. · NIH-10923285

This study is testing a new ankle prosthesis that helps people with severe ankle damage from injury or disease, aiming to improve their movement and reduce pain without needing amputation or fusion surgery, so they can enjoy daily activities more easily.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionFlex Orthopaedics, INC. NIH-funded
Lab location1 site (Calabasas, United States)
Project IDNIH-10923285 on NIH RePORTER

What this research studies

This research focuses on developing a Compliant Ankle Endoprosthesis designed to treat severe damage to the ankle and hindfoot caused by injury or disease. Current treatment options often lead to amputation or restrictive fusion surgeries, which can severely limit mobility and quality of life. The new prosthetic aims to restore function and alleviate pain without the need for fusion or amputation, potentially allowing patients to retain their limb while improving their ability to perform daily activities. The approach involves innovative engineering to create a device that mimics natural movement and provides support.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients suffering from severe ankle-hindfoot damage who are facing limited treatment options.

Not a fit: Patients with mild ankle-hindfoot conditions or those who are not candidates for prosthetic devices may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve mobility and quality of life for patients with severe ankle and hindfoot conditions.

How similar studies have performed: While the approach of using a compliant prosthetic device is innovative, similar concepts have shown promise in other areas of orthopedic treatment, suggesting potential for success.

Where this research is happening

Calabasas, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.