A new probiotic to help manage obesity and insulin resistance
Official title: A Novel Probiotic with The Potential for Long-term Management of Obesity and Insulin Resistance
Funded at Epic Nutrition for Y LLC · NIH-10919649 · Data updated 2026-11-12
This study is looking at a new probiotic called Clostridium cochlearium 2316 to see if it can help people manage obesity and insulin resistance by improving gut health through diet, offering a friendly and affordable way to support weight loss and better blood sugar control.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Epic Nutrition for Y LLC NIH-funded |
| Lab location | 1 site (Troy, United States) |
| Project start | September 15, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $194,275 |
| NIH project number | 1R41DK139815-01 |
| Project ID | NIH-10919649 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals struggling with obesity and insulin resistance, particularly those who have not found success with current treatment options.
✕Less likely to help
Patients who are not overweight or do not have insulin resistance may not benefit from this research.
What this research studies
This research investigates a novel probiotic strain, Clostridium cochlearium 2316, which may offer a long-term solution for managing obesity and insulin resistance. The approach focuses on dietary supplementation with this safe bacterium, which has shown promising results in preliminary studies by significantly reducing body weight gain and improving insulin sensitivity in animal models. The goal is to develop a non-invasive and cost-effective nutritional intervention that can alter the gut microbiome positively. Patients may benefit from a new dietary strategy that could complement existing obesity treatments.
Why it matters
Potential benefit: If successful, this research could provide a sustainable and effective method for managing obesity and insulin resistance in patients.
How similar studies have gone: Preliminary studies have shown success with similar probiotic approaches, indicating potential for this novel intervention.
Where this research is happening
-
Epic Nutrition for Y LLC
Troy, United States Active
Researchers
- Principal investigator: Zhou, Kequan — Epic Nutrition for Y LLC
- Study coordinator: Zhou, Kequan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.