A new probiotic to help manage obesity and insulin resistance

A Novel Probiotic with The Potential for Long-term Management of Obesity and Insulin Resistance

['FUNDING_OTHER'] · EPIC NUTRITION FOR Y LLC · NIH-10919649

This study is looking at a new probiotic called Clostridium cochlearium 2316 to see if it can help people manage obesity and insulin resistance by improving gut health through diet, offering a friendly and affordable way to support weight loss and better blood sugar control.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorEPIC NUTRITION FOR Y LLC (nih funded)
Locations1 site (TROY, UNITED STATES)
Trial IDNIH-10919649 on ClinicalTrials.gov

What this research studies

This research investigates a novel probiotic strain, Clostridium cochlearium 2316, which may offer a long-term solution for managing obesity and insulin resistance. The approach focuses on dietary supplementation with this safe bacterium, which has shown promising results in preliminary studies by significantly reducing body weight gain and improving insulin sensitivity in animal models. The goal is to develop a non-invasive and cost-effective nutritional intervention that can alter the gut microbiome positively. Patients may benefit from a new dietary strategy that could complement existing obesity treatments.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals struggling with obesity and insulin resistance, particularly those who have not found success with current treatment options.

Not a fit: Patients who are not overweight or do not have insulin resistance may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a sustainable and effective method for managing obesity and insulin resistance in patients.

How similar studies have performed: Preliminary studies have shown success with similar probiotic approaches, indicating potential for this novel intervention.

Where this research is happening

TROY, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Adult-Onset Diabetes Mellitus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.