A new platform for analyzing brain cell development and function
Official title: Imaging and computational platform for integrated analysis of biodata
Funded at North Carolina State University Raleigh · NIH-10980353 · Data updated 2026-11-12
This study is looking at how special brain cells called glial cells work and change when the brain is hurt or affected by diseases like Alzheimer's, using mice to help find new ways to treat these conditions that could eventually help patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina State University Raleigh NIH-funded |
| Lab location | 1 site (Raleigh, United States) |
| Project start | September 12, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $538,523 |
| NIH project number | 1R01NS134593-01A1 |
| Project ID | NIH-10980353 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with neurodegenerative diseases such as Alzheimer's or Alexander disease.
✕Less likely to help
Patients with acute brain injuries or those not affected by neurodegenerative diseases may not receive direct benefits from this research.
What this research studies
This research focuses on developing a cutting-edge technological platform that allows for the detailed analysis of brain cells, specifically glial cells, which are crucial for brain health and function. By utilizing advanced imaging and computational techniques, the project aims to study how these cells develop and respond to injuries or diseases like Alzheimer's and Alexander disease. The approach involves using mouse models to explore the mechanisms of glial cell production and their role in neurodegenerative conditions, providing insights that could lead to new therapeutic strategies. Patients may benefit from the findings as they could lead to breakthroughs in understanding and treating various brain disorders.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for neurodegenerative diseases by enhancing our understanding of brain cell development.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques to study brain cell dynamics, suggesting that this approach could yield valuable insights.
Where this research is happening
-
North Carolina State University Raleigh
Raleigh, United States Active
Researchers
- Principal investigator: Greenbaum, Alon — North Carolina State University Raleigh
- Study coordinator: Greenbaum, Alon
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.