A new platform for advanced proton therapy in lung cancer treatment
Official title: Open IPO and QA platform for conformal FLASH proton therapy
Funded at Emory University · NIH-11122784 · Data updated 2026-11-12
This study is looking at a new way to make proton therapy for central lung cancer safer and more effective, so patients can get better treatment with fewer side effects.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | June 20, 2025 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $158,899 |
| NIH project number | 1R03CA300834-01 |
| Project ID | NIH-11122784 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with central lung cancer who are seeking advanced treatment options.
✕Less likely to help
Patients with lung cancer types that do not involve central lesions or those who are not candidates for proton therapy may not benefit from this research.
What this research studies
This research focuses on improving proton therapy for central lung cancer by developing an innovative platform that optimizes treatment delivery. It aims to reduce damage to surrounding healthy organs while effectively targeting tumors. The approach combines advanced techniques to minimize toxicity and enhance the immune response, addressing critical challenges in current treatment methods. Patients may benefit from a more effective and safer treatment option that reduces the risk of severe side effects.
Why it matters
Potential benefit: If successful, this research could provide lung cancer patients with a safer and more effective treatment option that minimizes damage to healthy tissues.
How similar studies have gone: Other research has shown promise in using advanced proton therapy techniques, but this specific approach is innovative and largely untested.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Lin, Liyong — Emory University
- Study coordinator: Lin, Liyong
Related research
Other NIH-funded projects on the same topics.
-
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-
Efficient AI-Driven Image Guidance for Upright Lung Proton Therapy
A patient-focused AI-powered system helps guide upright proton therapy for lung cancer to improve accuracy and accessibility.
-
3D in vivo dosimetry for FLASH proton therapy
A new protoacoustic dosimeter will help doctors precisely measure dose delivery in proton FLASH therapy for adults with cancer.
-
Dose-LET Volume Histogram to Improve Safe Proton Therapy in Head and Neck Cancer
A Mayo Clinic study will develop a new tool to map dose and LET in spot-scanning proton therapy to reduce severe side effects for head and neck patients.
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AI-guided proton therapy that adapts during treatment for head and neck cancer
Using AI to build 3D images from routine X-rays so proton therapy can be updated during treatment for people with head and neck cancer.
-
Real-time guided proton radiation for more precise liver tumor treatment
Trying a proton radiation approach that tracks liver tumors in real time to treat people with liver cancer more precisely while protecting healthy liver tissue.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.