A new paper test for early detection of colorectal cancer.

Multiplexed Paper-Based Blood Test for Early-Stage Colorectal Cancer Screening

NIH-funded research Ohio State University · NIH-10757644

This study is working on a simple and affordable paper test that can help people check for early signs of colorectal cancer at home, making it easier for those who might not usually get screened to take charge of their health.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionOhio State University NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project IDNIH-10757644 on NIH RePORTER

What this research studies

This research aims to develop a simple and cost-effective paper-based blood test that can detect early-stage colorectal cancer (CRC) biomarkers. The approach involves using a 3D microfluidic device to multiplex the detection of five specific cancer antigens, which could allow for self-testing at home. Patients would send their samples to a central facility for analysis, potentially increasing screening rates among underserved populations. The goal is to improve accessibility and accuracy in CRC screening, particularly for those who may not have regular access to healthcare.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals at risk for colorectal cancer, particularly those from minority, uninsured, or low-income backgrounds.

Not a fit: Patients who are not at risk for colorectal cancer or those who have already been diagnosed with advanced stages of the disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a more accessible and accurate method for early detection of colorectal cancer, potentially saving lives.

How similar studies have performed: Other research has shown promise in developing similar diagnostic approaches, but this specific method is novel and untested.

Where this research is happening

Columbus, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer Antigen 125Cancersneoplasm/cancerEpithelial cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.