A new paper test for early detection of colorectal cancer.
Official title: Multiplexed Paper-Based Blood Test for Early-Stage Colorectal Cancer Screening
Funded at Ohio State University · NIH-10757644 · Data updated 2026-11-12
This study is working on a simple and affordable paper test that can help people check for early signs of colorectal cancer at home, making it easier for those who might not usually get screened to take charge of their health.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | December 26, 2022 |
| Project end | November 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $169,425 |
| NIH project number | 5R21CA270727-02 |
| Project ID | NIH-10757644 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at risk for colorectal cancer, particularly those from minority, uninsured, or low-income backgrounds.
✕Less likely to help
Patients who are not at risk for colorectal cancer or those who have already been diagnosed with advanced stages of the disease may not benefit from this research.
What this research studies
This research aims to develop a simple and cost-effective paper-based blood test that can detect early-stage colorectal cancer (CRC) biomarkers. The approach involves using a 3D microfluidic device to multiplex the detection of five specific cancer antigens, which could allow for self-testing at home. Patients would send their samples to a central facility for analysis, potentially increasing screening rates among underserved populations. The goal is to improve accessibility and accuracy in CRC screening, particularly for those who may not have regular access to healthcare.
Why it matters
Potential benefit: If successful, this research could lead to a more accessible and accurate method for early detection of colorectal cancer, potentially saving lives.
How similar studies have gone: Other research has shown promise in developing similar diagnostic approaches, but this specific method is novel and untested.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Badu-Tawiah, Abraham — Ohio State University
- Study coordinator: Badu-Tawiah, Abraham
Related research
Other NIH-funded projects on the same topics.
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Improving colorectal cancer screening and follow-up care.
This study is working to help more people get screened for colorectal cancer and receive the follow-up care they need, especially those who haven't been screened much before, so that everyone can have better access to important health checks and improve their overall health.
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Making colorectal cancer screening easier and more likely to happen
This project uses default options, simpler choices, and direct outreach to help average-risk adults who are overdue complete colorectal cancer screening with colonoscopy or stool tests.
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AI/AN Tailoring of a Home-Based Cervical and Colorectal Cancer Screening Program
A tailored, home-based cancer screening program helps AI/AN adults screen for cervical and colorectal cancer from home using self-collection tests and culturally aligned education.
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Bringing colorectal cancer screening to adults 45–54 who haven’t been screened
A grant to help low-income adults aged 45–54 start colorectal cancer screening through the Boston area’s community health centers.
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Increasing follow-up colonoscopies after a positive FIT in community clinics
Aims to help people with abnormal stool tests for colorectal cancer get timely follow-up colonoscopies in safety-net clinics.
-
Colorectal cancer screening with real-time imaging that may replace sedated scopes
Researchers are testing a new imaging method called optical coherence tomography (OCT) to spot and treat colon polyps without the need for sedation during a screening colonoscopy.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.