A new paper-based test for detecting cervical cancer using CRISPR technology
Low-Cost CRISPR-on-Paper for Cervical Cancer Screening at the Point of Care
This study is working on a simple and affordable test that can quickly check for high-risk HPV, which can lead to cervical cancer, so that it can be used right in your doctor's office or clinic without needing fancy equipment.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Connecticut Sch of Med/dnt NIH-funded |
| Lab location | 1 site (Farmington, United States) |
| Project ID | NIH-11080323 on NIH RePORTER |
What this research studies
This research aims to create a low-cost, easy-to-use diagnostic tool for cervical cancer screening that can be used directly at the point of care. It focuses on developing a paper-based platform that utilizes CRISPR technology to detect high-risk HPV types, which are responsible for cervical cancer. The test is designed to be simple and rapid, eliminating the need for expensive laboratory equipment and complex procedures. By using a hand warmer to generate heat, the test can be performed without any electronic devices, making it accessible in low-resource settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are women in low-resource settings who are at risk for cervical cancer and require accessible screening options.
Not a fit: Patients who are not at risk for cervical cancer or those who have already been diagnosed with the disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve early detection of cervical cancer, particularly in low- and middle-income countries.
How similar studies have performed: Other research has shown promise in using CRISPR technology for diagnostics, indicating that this approach could be effective, though the specific application of CRISPR-on-paper for cervical cancer screening is relatively novel.
Where this research is happening
Farmington, United States
- University of Connecticut Sch of Med/dnt — Farmington, United States (Active)
Researchers
- Principal investigator: Liu, Changchun — University of Connecticut Sch of Med/dnt
- Study coordinator: Liu, Changchun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.