A new oral medication to improve flu vaccine effectiveness in older adults
7HP349, an oral integrin activator to augment effectiveness of pre-exposure influenza vaccination
['FUNDING_SBIR_2'] · 7 HILLS PHARMA, LLC · NIH-10832641
This study is looking at a new pill called 7HP349 that might help older adults get better protection from the flu vaccine by boosting their immune response, and participants will take this pill along with their flu shot to see how it works.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | 7 HILLS PHARMA, LLC (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10832641 on ClinicalTrials.gov |
What this research studies
This research investigates a novel oral integrin activator called 7HP349, which aims to enhance the effectiveness of pre-exposure influenza vaccinations specifically for older adults. The study focuses on addressing the challenges faced by seniors, who often have a weaker immune response to standard flu vaccines. By improving the interaction between immune cells and the vaccine, the research seeks to boost T cell responses, which are crucial for effective immunity. Participants may receive this medication alongside their flu vaccine to assess its impact on their immune response.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above who are at higher risk for influenza-related complications.
Not a fit: Patients under the age of 65 or those with certain contraindications to flu vaccination may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective flu vaccinations for older adults, reducing hospitalizations and deaths related to influenza.
How similar studies have performed: Previous research has shown that enhancing immune responses in older adults can improve vaccine effectiveness, suggesting that this approach may hold promise.
Where this research is happening
HOUSTON, UNITED STATES
- 7 HILLS PHARMA, LLC — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MARATHI, UPENDRA — 7 HILLS PHARMA, LLC
- Study coordinator: MARATHI, UPENDRA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.