A new nonanimal test for detecting eye irritants in products

IVD EIT a Nonanimal Kit and Service for the Detection of Ocular Irritants: Phase II

NIH-funded research Lebrun Labs, LLC · NIH-10839465

This study is working on a new way to test if products are safe for your eyes without using animals, so that everyone can enjoy safer products that have been carefully checked for irritation.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionLebrun Labs, LLC NIH-funded
Lab location1 site (Anaheim, United States)
Project IDNIH-10839465 on NIH RePORTER

What this research studies

This research focuses on developing a nonanimal test called the in vitro depth of injury eye irritation test (IVD EIT) to identify ocular irritants in consumer products. The goal is to create a reliable method that can accurately classify all levels of ocular irritants without using live animals, addressing the need for safer testing alternatives due to new regulations. By utilizing advanced methodologies, the research aims to improve the sensitivity and specificity of irritation detection, ensuring better safety labeling for consumers and manufacturers. Patients may benefit from safer products that have been tested without animal harm.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals concerned about the safety of consumer products, particularly those with sensitivities to eye irritants.

Not a fit: Patients who are not affected by eye irritants or do not use consumer products that may cause ocular irritation may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer consumer products by providing accurate testing for eye irritants without the use of animals.

How similar studies have performed: Other research has shown promise in developing nonanimal testing methods, but this specific approach is novel and aims to fill a critical gap in ocular irritation testing.

Where this research is happening

Anaheim, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.