NIH-funded research Sbir 2 grant

A new nonanimal test for detecting eye irritants in products

Official title: IVD EIT a Nonanimal Kit and Service for the Detection of Ocular Irritants: Phase II

Funded at Lebrun Labs, LLC · NIH-10839465 · Data updated 2026-11-12

This study is working on a new way to test if products are safe for your eyes without using animals, so that everyone can enjoy safer products that have been carefully checked for irritation.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionLebrun Labs, LLC
NIH-funded
Lab location1 site (Anaheim, United States)
Project startMay 10, 2023
Project endApril 30, 2026
Funding year2024
Award (this year)$913,819
NIH project number5R44ES031881-03
Project IDNIH-10839465 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals concerned about the safety of consumer products, particularly those with sensitivities to eye irritants.

Less likely to help

Patients who are not affected by eye irritants or do not use consumer products that may cause ocular irritation may not receive benefit from this research.

What this research studies

This research focuses on developing a nonanimal test called the in vitro depth of injury eye irritation test (IVD EIT) to identify ocular irritants in consumer products. The goal is to create a reliable method that can accurately classify all levels of ocular irritants without using live animals, addressing the need for safer testing alternatives due to new regulations. By utilizing advanced methodologies, the research aims to improve the sensitivity and specificity of irritation detection, ensuring better safety labeling for consumers and manufacturers. Patients may benefit from safer products that have been tested without animal harm.

Why it matters

Potential benefit: If successful, this research could lead to safer consumer products by providing accurate testing for eye irritants without the use of animals.

How similar studies have gone: Other research has shown promise in developing nonanimal testing methods, but this specific approach is novel and aims to fill a critical gap in ocular irritation testing.

Where this research is happening

  • Lebrun Labs, LLC
    Anaheim, United States
    Active

Researchers

  • Principal investigator: Lebrun, Stewart — Lebrun Labs, LLC
  • Study coordinator: Lebrun, Stewart

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.