NIH-funded research Sbir 2 grant

A new non-hormonal contraceptive device for men

Official title: Development of ADAM Air: A Non-Hormonal Vas Occlusive Contraceptive Device

Funded at Contraline, INC. · NIH-10929569 · Data updated 2026-11-12

This study is testing a new, non-hormonal birth control option for men called ADAM Air, which involves a small implant that blocks sperm from being released, offering a safe and reversible way to prevent pregnancy.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionContraline, INC.
NIH-funded
Lab location1 site (Charlottesville, United States)
Project startSeptember 10, 2024
Project endAugust 31, 2025
Funding year2024
Award (this year)$291,440
NIH project number1R44HD115509-01
Project IDNIH-10929569 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are men seeking a non-hormonal contraceptive method.

Less likely to help

Patients who are not male or those who do not wish to use a contraceptive method will not benefit from this research.

What this research studies

This research focuses on developing ADAM Air, a non-hormonal contraceptive device designed for men. It involves implanting an aerogel into the vas deferens, which then swells to block sperm from reaching the ejaculatory duct. This innovative approach aims to provide a long-lasting and reversible contraceptive option, addressing the need for more male contraceptive methods. The study builds on previous findings that demonstrated the safety and efficacy of the first-generation ADAM device.

Why it matters

Potential benefit: If successful, this research could provide men with a reliable and reversible contraceptive option, potentially reducing unintended pregnancies.

How similar studies have gone: Previous studies on the first-generation ADAM device have shown promising results, indicating that this new approach may also be effective.

Where this research is happening

  • Contraline, INC.
    Charlottesville, United States
    Active

Researchers

  • Principal investigator: Tropsha, Yelena — Contraline, INC.
  • Study coordinator: Tropsha, Yelena

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.