A new nanodrug for endometriosis pain and lesions

Development of anti-inflammatory nanodrug for endometriosis treatment

['FUNDING_R01'] · MICHIGAN STATE UNIVERSITY · NIH-11141616

This project explores a new non-hormonal nanodrug to reduce inflammation and lesions in women with endometriosis.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMICHIGAN STATE UNIVERSITY (nih funded)
Locations1 site (EAST LANSING, UNITED STATES)
Trial IDNIH-11141616 on ClinicalTrials.gov

What this research studies

Endometriosis affects many women, causing chronic pain and infertility, and current treatments often have side effects or don't prevent recurrence. This research focuses on a new approach using tiny particles called nanoceria, which act as powerful anti-inflammatory agents. These nanoparticles are designed to specifically target and accumulate in endometriosis lesions, helping to reduce inflammation and shrink the lesions. Early findings in animal models suggest this nanodrug can significantly lessen the number of endometriosis lesions.

Who could benefit from this research

Good fit: This research is relevant for women experiencing endometriosis, especially those with chronic pelvic pain and infertility who are seeking new treatment options.

Not a fit: Patients without endometriosis or those whose condition is well-managed by existing treatments may not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this nanodrug could offer a new, non-hormonal treatment option for endometriosis that specifically targets lesions and reduces pain with fewer side effects.

How similar studies have performed: Preliminary results in mouse models have shown that this specific nanodrug can reduce endometriotic lesions, indicating a promising new direction.

Where this research is happening

EAST LANSING, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.