A new model to test treatments for HIV and SIV
A dual-purpose hu-mouse model for evaluating SIV and HIV cure strategies
This study is creating a special type of mouse that has a human immune system to help test new medicines for HIV and SIV, making it easier and cheaper to find effective treatments before trying them in more complex animals.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Colorado State University NIH-funded |
| Lab location | 1 site (Fort Collins, United States) |
| Project ID | NIH-10652685 on NIH RePORTER |
What this research studies
This research aims to develop a small animal model that can be used to evaluate new drugs for treating HIV and SIV. By using humanized mice that have a human immune system, researchers can test the effectiveness of promising treatments before moving on to more expensive and limited non-human primate models. This approach could streamline the drug testing process and provide valuable insights into potential cures for these viruses. The study focuses on both HIV and SIV, allowing for simultaneous testing of therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV or at high risk of HIV infection.
Not a fit: Patients who are not infected with HIV or SIV may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments and potentially cures for HIV and SIV.
How similar studies have performed: Other research has shown success in using animal models for HIV studies, making this approach promising but still innovative.
Where this research is happening
Fort Collins, United States
- Colorado State University — Fort Collins, United States (Active)
Researchers
- Principal investigator: Akkina, Ramesh — Colorado State University
- Study coordinator: Akkina, Ramesh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.