NIH-funded research R21 grant

A new model to predict malaria transmission based on environmental factors

Official title: A Novel Hydrology-based Malaria Transmission Model and Field Applications

Funded at University of California-Irvine · NIH-10735900 · Data updated 2026-11-12

This study looks at how things like water and weather affect where mosquitoes that spread malaria live, so we can find better ways to control them and help keep people safe from malaria in Africa.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine
NIH-funded
Lab location1 site (Irvine, United States)
Project startNovember 7, 2022
Project endOctober 31, 2025
Funding year2024
Award (this year)$196,250
NIH project number5R21AI174183-02
Project IDNIH-10735900 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals living in malaria-endemic regions of Africa, particularly in areas where current control measures are failing.

Less likely to help

Patients living outside of malaria-endemic regions or those not affected by malaria will not benefit from this research.

What this research studies

This research investigates how environmental factors influence malaria transmission in Africa, focusing on the development of a hydrology-based model. By predicting where mosquito larvae thrive, the study aims to improve vector control strategies, particularly larval source management (LSM). The approach combines field data and environmental modeling to identify optimal areas for intervention, potentially enhancing the effectiveness of malaria control efforts. The research seeks to address the limitations of current malaria prevention methods, such as insecticide-treated nets and indoor residual spraying.

Why it matters

Potential benefit: If successful, this research could lead to more effective malaria control strategies, reducing the incidence of malaria in affected regions.

How similar studies have gone: Previous research has shown promise in using environmental modeling for vector control, but this specific hydrology-based approach is relatively novel.

Where this research is happening

  • University of California-Irvine
    Irvine, United States
    Active

Researchers

  • Principal investigator: Yan, Guiyun — University of California-Irvine
  • Study coordinator: Yan, Guiyun

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.