A new minimally invasive treatment for overactive bladder
Official title: Clinical readiness of Uzap - the minimally invasive Overactive Bladder treatment
Funded at Stellartech Research Corporation · NIH-10874601 · Data updated 2026-11-12
This study is testing a new device called the NewUro Uzap, which provides a quick and gentle treatment for people with overactive bladder to help reduce the urge to urinate and improve their daily life, all without needing medications or surgery.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stellartech Research Corporation NIH-funded |
| Lab location | 1 site (Milpitas, United States) |
| Project start | September 20, 2021 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $728,341 |
| NIH project number | 5R44DK130724-03 |
| Project ID | NIH-10874601 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who experience symptoms of overactive bladder.
✕Less likely to help
Patients with other underlying bladder conditions or those who are not responsive to minimally invasive treatments may not benefit from this research.
What this research studies
This research focuses on developing the NewUro Uzap device, which offers a minimally invasive, single-session treatment for overactive bladder (OAB). The Uzap device uses transurethral radiofrequency mucosal partitioning to alleviate symptoms without the need for drugs or implants. By targeting excessive electrical connectivity in the bladder mucosa, the device aims to reduce the frequency of urges to urinate and improve overall bladder function. Patients will be monitored for outcomes related to symptom relief and quality of life improvements.
Why it matters
Potential benefit: If successful, this research could provide a long-lasting, effective treatment option for patients suffering from overactive bladder.
How similar studies have gone: Previous research has shown promise with similar minimally invasive approaches, indicating potential for success with the Uzap device.
Where this research is happening
-
Stellartech Research Corporation
Milpitas, United States Active
Researchers
- Principal investigator: Stern, Roger — Stellartech Research Corporation
- Study coordinator: Stern, Roger
Related research
Other NIH-funded projects on the same topics.
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Microneedle delivery of Trospium for better tolerance in overactive bladder
A tiny, painless microneedle patch is being developed to deliver Trospium chloride more comfortably for people with overactive bladder.
-
Alternatives to Step Therapy for Overactive Bladder in Older Adults
This grant explores simpler, patient-centered ways to treat overactive bladder in people 65 and older, to help them get effective care faster.
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Culturally tailored AI-assisted digital therapy for bladder symptoms in Black women
A new AI-powered app called CeCe helps Black women learn about overactive bladder and manage its symptoms with education and coaching.
-
Predicting risks and outcomes of advanced overactive bladder treatments for older adults
This project will build a tool to predict which third-line treatments for overactive bladder are likely to help or harm older and frail adults.
-
Personalized brain stimulation for overactive bladder in multiple sclerosis
This research uses targeted, noninvasive brain stimulation to try to reduce urinary urgency, frequency, and leakage in women with multiple sclerosis.
-
Long-lasting bladder treatment for urinary leaks and urgency in older adults
This project is creating bladder-instilled medicines that aim to give months of relief from urinary leaks and urgent urges in older adults who haven't been helped by current treatments.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.