A new microscope that can quickly record and stimulate brain activity.
An Autonomous Rapidly Adaptive Multiphoton Microscope for Neural Recording and Stimulation
['FUNDING_OTHER'] · JOHNS HOPKINS UNIVERSITY · NIH-10739050
This study is working on a special microscope that helps scientists see and understand how brain cells communicate with each other, which could lead to better treatments for neurological conditions.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10739050 on ClinicalTrials.gov |
What this research studies
This research focuses on developing an advanced multiphoton microscope that utilizes genetically encoded calcium indicators to observe and stimulate neurons in the brain. By improving the speed and efficiency of neuronal recordings, the microscope aims to capture fine details of neuronal activity across multiple circuits simultaneously. The innovative approach combines optimized scanning techniques with advanced fluorescence methods to enhance the temporal resolution of brain activity mapping. Patients may benefit from insights gained into brain function and potential new treatments for neurological conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with neurological conditions or those interested in brain function studies.
Not a fit: Patients with conditions unrelated to brain function or those not residing near the research location may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding brain function and developing new therapies for neurological disorders.
How similar studies have performed: Other research has shown promising results with advanced imaging techniques, indicating potential for success in this novel approach.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FOSTER, MARK A — JOHNS HOPKINS UNIVERSITY
- Study coordinator: FOSTER, MARK A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.