A new method to restore vision using light-activated nanoparticles.
Plasmonic Retinal Prosthesis
['FUNDING_R01'] · BROWN UNIVERSITY · NIH-10683362
This study is exploring a new way to help people regain their vision using tiny gold particles and special light, which could be a gentler and more effective option than current methods, making it easier for patients to see better without needing major surgery.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BROWN UNIVERSITY (nih funded) |
| Locations | 1 site (PROVIDENCE, UNITED STATES) |
| Trial ID | NIH-10683362 on ClinicalTrials.gov |
What this research studies
This research investigates a novel approach to restore vision through a plasmonic retinal prosthesis that utilizes gold nanoparticles and near-infrared light. By generating localized heat without causing bulk tissue heating, this method aims to activate neurons in the retina more effectively than traditional electrode-based prostheses. The study focuses on optimizing and validating this technology to enhance visual resolution and reduce the need for invasive surgical procedures. Patients may benefit from a less invasive option for vision restoration that could lead to improved outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from retinal diseases or disorders that lead to vision loss.
Not a fit: Patients with non-retinal causes of vision loss or those who do not have access to the required technology may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a less invasive and more effective method for restoring vision in patients with retinal disorders.
How similar studies have performed: While electrode-based retinal prostheses have shown clinical promise, this plasmonic approach is novel and has not yet been tested in a clinical setting.
Where this research is happening
PROVIDENCE, UNITED STATES
- BROWN UNIVERSITY — PROVIDENCE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEE, JONGHWAN — BROWN UNIVERSITY
- Study coordinator: LEE, JONGHWAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.