A new method to restore bone loss caused by gum disease
Official title: A novel bioengineering approach to restoring permanent periodontal inflammatory bone loss
Funded at Brigham and Women's Hospital · NIH-11077887 · Data updated 2026-11-12
This study is working on a new type of bone implant to help people with gum disease who have lost bone in their jaws, using advanced materials and 3D printing to make it safer and more effective for restoring dental health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $814,498 |
| NIH project number | 5R01DE032406-03 |
| Project ID | NIH-11077887 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing alveolar bone loss due to chronic periodontal disease.
✕Less likely to help
Patients with non-inflammatory bone loss or those who do not have periodontal disease may not benefit from this research.
What this research studies
This research focuses on developing a novel bioengineering approach to address alveolar bone loss due to periodontal disease, which affects a significant portion of the population. The project aims to create a next-generation bone implant that can effectively regenerate bone in chronic inflammatory conditions, overcoming the limitations of current grafting techniques. By utilizing advanced materials and 3D printing technology, the research seeks to enhance bone formation capacity and reduce complications associated with traditional grafts. Patients suffering from periodontitis may benefit from this innovative solution that aims to restore their dental health and improve their quality of life.
Why it matters
Potential benefit: If successful, this research could provide a more effective treatment option for patients suffering from periodontal disease, potentially restoring their dental function and overall health.
How similar studies have gone: Previous research has shown promise in using bioengineering approaches for bone regeneration, indicating potential success for this novel method.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Jang, Hae Lin — Brigham and Women's Hospital
- Study coordinator: Jang, Hae Lin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.