A new method to restore bone loss caused by gum disease

A novel bioengineering approach to restoring permanent periodontal inflammatory bone loss

NIH-funded research Brigham and Women's Hospital · NIH-11077887

This study is working on a new type of bone implant to help people with gum disease who have lost bone in their jaws, using advanced materials and 3D printing to make it safer and more effective for restoring dental health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11077887 on NIH RePORTER

What this research studies

This research focuses on developing a novel bioengineering approach to address alveolar bone loss due to periodontal disease, which affects a significant portion of the population. The project aims to create a next-generation bone implant that can effectively regenerate bone in chronic inflammatory conditions, overcoming the limitations of current grafting techniques. By utilizing advanced materials and 3D printing technology, the research seeks to enhance bone formation capacity and reduce complications associated with traditional grafts. Patients suffering from periodontitis may benefit from this innovative solution that aims to restore their dental health and improve their quality of life.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing alveolar bone loss due to chronic periodontal disease.

Not a fit: Patients with non-inflammatory bone loss or those who do not have periodontal disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a more effective treatment option for patients suffering from periodontal disease, potentially restoring their dental function and overall health.

How similar studies have performed: Previous research has shown promise in using bioengineering approaches for bone regeneration, indicating potential success for this novel method.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.