A new method to repair torn anterior cruciate ligaments in the knee.
CollaLink: Guided-regenerative Scaffold for Augmentation of Anterior Cruciate Ligament Repair
This study is testing a new type of implant called CollaLink, made from strong collagen threads, to help people with certain types of torn ACLs in their knees heal better during surgery while keeping their own tissue intact and lowering the chances of future problems like arthritis.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Collamedix INC. NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10760639 on NIH RePORTER |
What this research studies
This research focuses on developing a novel biotextile implant called CollaLink, designed to enhance the repair of torn anterior cruciate ligaments (ACLs) in the knee. The approach aims to utilize high-strength pure-collagen threads to create a tubular braid that can be easily applied over the ACL tear during surgery. By enabling primary repair of mid-substance ACL tears, this method seeks to preserve the patient's native tissue and reduce the risk of long-term complications such as osteoarthritis. The research is particularly relevant for patients with specific types of ACL tears that are currently difficult to repair effectively.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have sustained mid-substance tears of the anterior cruciate ligament.
Not a fit: Patients with proximal ACL tears or those who have other knee injuries unrelated to ACL tears may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved surgical outcomes and reduced long-term knee problems for patients with ACL tears.
How similar studies have performed: While there have been advancements in ACL repair techniques, this specific approach using a biologic augmentation for mid-substance tears is novel and has not been tested in previous studies.
Where this research is happening
Cleveland, United States
- Collamedix INC. — Cleveland, United States (Active)
Researchers
- Principal investigator: Shankar, Subba — Collamedix INC.
- Study coordinator: Shankar, Subba
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.