A new method to quickly extract brain-related particles from blood for Alzheimer's and ALS diagnosis
Official title: A nanosized magnetic particle system for fast and efficient neuronal extracellular vesicle enrichment from plasma
Funded at Captis Diagnostics · NIH-10820640 · Data updated 2026-11-12
This study is working on a new way to quickly and easily collect tiny particles from your blood that can help doctors find signs of brain diseases like Alzheimer's and ALS, making it easier to check your brain health without needing invasive tests.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Captis Diagnostics NIH-funded |
| Lab location | 1 site (Pittsburgh, UNITED STATES) |
| Project start | September 18, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $306,509 |
| NIH project number | 1R43AG085732-01 |
| Project ID | NIH-10820640 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk for or diagnosed with Alzheimer's disease or ALS.
✕Less likely to help
Patients with neurological conditions not related to Alzheimer's or ALS may not benefit from this research.
What this research studies
This research focuses on developing a novel technology to efficiently isolate neuronal extracellular vesicles (EVs) from blood plasma. These EVs contain important biomarkers that can indicate the presence of neurological diseases such as Alzheimer's and ALS. By using nanosized magnetic particles, the researchers aim to create a system that allows for rapid and effective extraction of these vesicles, providing a minimally invasive way to access brain health information. This could lead to improved diagnostic methods for various neurodegenerative conditions.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnoses of Alzheimer's disease and ALS, improving patient outcomes.
How similar studies have gone: Other research has shown promise in using extracellular vesicles for diagnosing neurological diseases, indicating that this approach could be effective.
Where this research is happening
-
Captis Diagnostics
Pittsburgh, United States Active
Researchers
- Principal investigator: Milosevic, Jadranka — Captis Diagnostics
- Study coordinator: Milosevic, Jadranka
Related research
Other NIH-funded projects on the same topics.
-
Magnetic lipid nanoprobe platform to quickly and cheaply isolate extracellular vesicles from body fluids
A new magnetic lipid nanoprobe system aims to rapidly and affordably pull extracellular vesicles from common body fluids to aid disease diagnosis.
-
A new method for quickly isolating tiny vesicles from body fluids for disease diagnosis
This study is testing a new way to quickly and easily collect tiny particles from your blood, saliva, or urine that can help doctors spot diseases like cancer and heart problems without needing to do painful tissue samples.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.